Companies are becoming increasingly concerned about Brexit. This Quick Note frames the key dimensions of likely scenarios, including short-term and long-term impacts. As Brexit day approaches (March 29, 2019), it is important for businesses to be ready for various scenarios and make contingency plans. In this note we analyze what each scenario means for companies that have businesses that operate in—or trade with—the UK. We expect Brexit to affect businesses in six ways: supply chains, compliance with regulation, talent, innovation, currency volatility, and sales. Final Brexit will have implications for the UK economy, with knock-on implications for its major trading partners in Europe and elsewhere, for many years to come.