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The operational excellence challenge for 2017: prepare for global uncertainties. That means cost controls and a culture of excellence, say CEOs in our annual survey. In such a culture, employees are lifted and equipped with the incentives and skills to achieve. While small and large companies and mature and emerging economies may differ in their approaches, their goals are similar: Meet the digital transformation challenge and increase employee engagement, resilience, alignment, and agility. It’s a tall order that may require redesign of business processes.