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Brexit creates an existential crisis for the rest of the EU that will ultimately affect its economy and business climate. How and when the EU will overcome this crisis is impossible to say for certain given how fluid the situation is; however, we present four likely scenarios. In each scenario, some sectors and industries benefit more than others, given that growth drivers will change. With a tailwind from global growth and the will to reform its governance, the EU can reset its course—if it can find sufficient impetus to do so.